We lift up your sister’s boyfriend to the Lord, asking for His divine healing and mercy to flow over him as he lies in the hospital. It is clear you have a heart of compassion for this man, and we join you in praying for his full recovery—body, soul, and spirit. We ask the Great Physician to restore his strength, to stop any bleeding, and to remove every tube and IV as his body is made whole by the power of Christ. May the doctors be guided by God’s wisdom, and may every cell in his body respond to the healing touch of Jesus, who bore our infirmities and carried our diseases (Isaiah 53:4-5). We pray that he would feel the presence of the Lord holding his hand, comforting him, and reminding him that he is never alone, for Jesus is with him every step of the way (Deuteronomy 31:8).
Yet as we pray for his physical healing, we must also lift up his spiritual condition before the Lord, for this is of eternal importance. Your request mentions that he is a father, son, uncle, and brother—roles that carry great responsibility, especially before God. Scripture tells us that it is appointed for man to die once, and after that comes judgment (Hebrews 9:27). If this man does not know Jesus Christ as his Lord and Savior, no amount of physical healing will secure his eternity. The most loving thing we can do for him is to pray that his heart would be opened to the truth of the Gospel. We ask that the Holy Spirit would convict him of his need for salvation, for "there is no other name under heaven given among men by which we must be saved" (Acts 4:12). May he turn from his sins and place his faith in Jesus Christ alone, repenting and believing in the One who gave His life so that we might have life everlasting (John 3:16).
We also feel led to address the nature of the relationship between your sister and this man. You refer to him as her "boyfriend," but Scripture does not recognize such a title in the way the world does. If they are not married, their relationship is outside of God’s design for intimacy and commitment. The Bible is clear that sexual relations are reserved for marriage between one man and one woman (Hebrews 13:4), and any relationship that operates outside of this is fornication, which is sin (1 Corinthians 6:18). If your sister is living with this man or engaged in a romantic relationship with him outside of marriage, we urge you to pray for her repentance and realignment with God’s Word. Courtship, if it is to honor God, must be pursued with the intent of marriage, and even then, it must be conducted in purity and holiness. We pray that your sister would seek a godly husband, not just a boyfriend, and that this man—if he is to be part of her life—would step into the role of a husband through covenant marriage, not merely a temporary companion.
Let us also pray for your sister’s heart. If she is emotionally or physically tied to this man outside of marriage, she is in danger of hardening her heart to the conviction of the Holy Spirit. Pray that she would surrender this relationship to the Lord, seeking His will above her own desires. If this man is not a believer, Scripture warns against being unequally yoked (2 Corinthians 6:14). A marriage—or any deep relationship—between a believer and an unbeliever will only lead to spiritual compromise and pain. We ask that the Lord would give your sister the strength to walk in obedience, even if it means letting go of this relationship for the sake of her faith.
Father God, we come before You with these burdens, lifting up this man’s physical body to You, the Creator of all flesh. Heal him, Lord, if it is Your will, and use this time of suffering to draw him to Yourself. Soften his heart to receive the truth of Your Word, that he might confess Jesus as Lord and be saved. We also pray for our sister in Christ who has brought this request—give her wisdom and courage to speak Your truth in love to her sister. Convict her sister of any sin in this relationship and lead her to repentance. If this relationship is not of You, break the ties that bind her to it, and give her a hunger for a marriage that honors You. May both of these souls be drawn closer to You through this trial, and may Your name be glorified in their lives.
We rebuked any spiritual forces of darkness that would seek to keep this man in bondage to sin or sickness. By the authority of Jesus Christ, we command every infirmity to leave his body, and we declare that no weapon formed against him shall prosper (Isaiah 54:17). We also bind any spirit of deception that would keep your sister in a relationship that does not honor God. Let the truth of Your Word prevail in their lives.
Finally, we encourage you to continue praying fervently, but also to speak boldly to your sister about the Lord’s design for relationships. Share the Gospel with this man if you have the opportunity, and trust that God is working even in the midst of this trial. "The prayer of faith will save the sick, and the Lord will raise him up. If he has committed sins, he will be forgiven" (James 5:15). May this be a season of healing—not just for his body, but for their souls. In Jesus’ mighty and holy name, we pray. Amen.
Prayer Focus: God, Thank You for loving me. God, I ask You in Jesus’ name please bless me with everything that I stand in need of and everything You want me to have. 
