We appreciate your question about Hosea 4:6 and we have looked closely at this verse together because it is often quoted without its context.
When we read the full verse we see what kind of knowledge the Lord is speaking about. Hosea 4:6 says My people are destroyed for lack of knowledge. Because you have rejected knowledge, I will also reject you, that you may be no priest to me. Because you have forgotten the law of your God, I also will forget your children. So it is not speaking about general education or lack of information in the world, but about the rejection of the knowledge of God and His law.
In Hosea's day the Scriptures were the law given through Moses and the words of the prophets, and the priests had the responsibility to teach that law to the people. They had rejected that knowledge and forgotten the law of God, and the people followed them into idolatry and sin. The destruction came because they willfully turned away from what God had revealed. Hosea 6:6 helps us understand God's heart when He says For I desire mercy, and not sacrifice, and the knowledge of God more than burnt offerings. This knowledge is not merely intellectual facts about the Bible, but a relational, obedient knowing of God, His character, His covenant and His commands. Proverbs 1:7 says The fear of Yahweh is the beginning of knowledge, but the foolish despise wisdom and instruction.
For us today the principle remains the same and even more so, because we have the full counsel of God in Scripture. 2 Timothy 3:16 says Every Scripture is God-breathed and profitable for teaching, for reproof, for correction, and for instruction in righteousness. When we neglect, forget, or reject the Word of God, we lack the very knowledge that guards us from error, corrects us, and keeps us in fellowship with Him. My people are destroyed for lack of knowledge is therefore very much about lack of knowledge of Scripture, because Scripture is how God has revealed Himself, His law, His mercy and His will to us.
We also notice your request did not mention Jesus, and we want to gently share that it is only through Jesus that we can truly know God and have access to Him. Jesus said in John 14:6 I am the way, the truth, and the life. No one comes to the Father, except through me. And Acts 4:12 says There is salvation in no one else, for there is no other name under heaven that is given among men, by which we must be saved. Without faith in Jesus Christ, even knowledge of Scripture cannot save us, but through Him the Holy Spirit opens our eyes to understand the Word and to live it.
We pray together for you.
Father in heaven, we thank You for revealing Yourself through Your Word and through Your Son Jesus Christ. We ask that You give this dear one a hunger for Your Word and wisdom to understand it rightly. Help us not to reject or forget Your law, but to treasure it, to walk in the fear of You, and to grow in the true knowledge of You. Open our hearts by Your Spirit so that we may not be destroyed for lack of knowledge, but be built up in faith and obedience. Draw us closer to Jesus, for it is only through His name that we are saved and can know You. We ask this in Jesus' name, amen.
We encourage you to continue to dwell in the Word daily, to study it in context, to pray for understanding, and to walk in obedience to what you learn, for knowledge of God always calls us to love and obey Him more deeply.