Your heartfelt cry to see the Lord glorified in your family is beautiful and right, and God hears that prayer. He is gracious to invite you to call upon Him in the day of trouble as you have done, and He promises to answer, to be a refuge and shelter, and to let no weapon formed against His people ultimately prevail.
What you are describing is at its heart a spiritual battle. The real warfare we face is not against flesh and blood but against spiritual forces at work around us. Much of the heaviness, unsettled emotions, mental pressure, and opposition you feel is the overflow of that unseen conflict. That is why the battle cannot be fought with human methods or effort. God has given spiritual weapons for a spiritual war, and the Scriptures point to them clearly: His Word, faith in Christ, and prayer. The battle is so often for the mind, for control of thoughts and emotions, and it is there that the Word of God and persistent prayer bring victory as you trust Him and bring every thought under His truth.
In all of this the greatest need and the greatest miracle is salvation. The grace of God that brings salvation has appeared through Jesus Christ. His very name means the Lord is salvation, for He came to save His people from their sins. It is only through faith in Him as the spotless Lamb who takes away sin that we are cleansed and made right with God. If we confess with our mouth that Jesus is Lord and believe in our heart that God raised Him from the dead, we will be saved. That confession now brings salvation, and Scripture urges us not to delay, for now is the accepted time, now is the day of salvation. Your prayer for unsaved family members and relatives is exactly in line with God's heart. He desires all to come to repentance. Keep lifting them up, asking God to open their hearts to the gospel, to deliver from bondage, addiction, compulsion and every chain that is not of Him.
For those who have already believed, God calls us to work out what He has worked within us, with reverence and dependence. That does not mean working for our salvation, for salvation rests entirely on His grace and the finished work of Jesus and the faith He gives us to believe. It means living out in daily obedience the new life He has already placed inside, loving Him first, obeying Him, seeking His wisdom and direction, and asking to be filled with His Holy Spirit.
You have pleaded the blood of Jesus and asked for His protection around your family, your thoughts and emotions, and for His ministering angels to surround you. It is right to look to Christ alone for covering and deliverance and to ask Him to block what is not good and to establish His peace. He is your wall of protection. Continue to bring every specific burden to Him, the school needs and friendships and tests, the physical needs and spasms and wounds and burnout, the work pressures and meetings and planning and leadership decisions, the care needs and the desire for rest and restoration. He knows every detail you have lifted up, even those you could only mention briefly, and He invites you to cast all of it on Him.
Concerning healing, the Bible shows that Jesus has power over sickness and infirmity and that His suffering provides for both spiritual and physical healing. Yet healing comes in different ways. Sometimes it is immediate, sometimes it is gradual, as God has woven healing processes into our bodies which are themselves from Him, and sometimes, as with Paul's thorn in the flesh, God in His wisdom allows a trial to remain for a greater purpose while giving grace to endure. We can pray with confidence for healing for each person you named, for healing of bodies, minds, emotions, trauma, rejection and deep wounds, and for healing of relationships, while trusting His perfect will and timing. Whatever He does, remember that the forgiveness of sins is the greatest healing of all, and nothing compares to that gift.
Concerning relationships, we join you in praying for salvation and holiness. God's design for intimacy is within the lifelong covenant of marriage between one man and one woman. We will not ask God to bless what is outside that design, but we do ask Him to save, to convict, to bring repentance, and to graciously block any relationship that would lead away from Him, and to lead each person into purity and wholeness in Christ. Where there has been hurt, lies, strongholds and broken fellowship, we ask Him to rebuke what is evil, to expose what needs to be exposed, to remove what is harmful, and to bring supernatural restoration where it is His will.
You confessed failing often and needing mercy. His mercies are indeed new every morning. He is faithful to forgive when we repent of what grieves Him, and to cleanse and guide us. When you have spoken in frustration or vented about others, bring that to Him in confession and He will forgive and help you make it right and turn even that into good. He will give wisdom for how to respond, how to lead and shepherd, how to handle what angers you in a way that honors Him, and how to find motivation and strength again for work and daily duties when you feel out of it and weary.
God promises to hear those who cry out to Him day and night, and to act. He will fight your battles as you trust Him and use the weapons He has provided. Keep standing on His Word, keep praying, keep believing. He who has begun a good work will be faithful to complete it.
We pray with you now: Lord Jesus, be glorified in this family. Save those who do not yet know You, deliver those in bondage, heal those who are sick and wounded in body and soul, and protect all under Your covering. Surround this home with Your presence, guard thoughts and emotions, grant peace, grant friends and favor where needed, grant help with school and work and every responsibility, confront evil and lies, heal relationships, prevent what would harm, and turn what the enemy meant for evil into blessing. Teach us to repent quickly, to be filled with Your Spirit, to love You above all and to walk in wisdom. We thank You for Your new mercies each morning and for answered prayer, and we trust You to do what only You can do. In Your name, the Lord our salvation, amen.