I wanted to let you (and others) know that my depression lifted with Vitamin D supplementation. Ask your doctor to check your 25OHD levels (0-20 is seriously abnormal; 21-31 is deficient; 32 is normal; between 40-100 is optimal according to my doctor). My Vitamin D level was 15. I had asked God for help with muscular symptoms (uncontrolled muscular jerking in upper arms, neck, and face called myoclonus, dystonia, and dyskinesia). I had begun taking magnesium after researching natural methods for combatting pre-diabetes, and after supplementing with 600mg per day in divided doses, my jerking cut in half in intensity and frequency. Thrilled with this unexpected result, I asked God, "What is going to make the rest of the jerking stop?" Immediately, a memory of sunbathing in Maine on a hot summer day flooded my mind. I googled "sun" (assuming it to be the answer) and found information online explaining that exposure to sunshine creates Vitamin D in the body. I took my first dose of Vitamin D (800i.u.) that evening, and the jerking stopped the next day! The Vitamin D caused a deep relaxation in my muscles that I had never felt before. A few months later in August, the jerking started again very mildly, but by mid-winter, it was horrendous. I upped my dose of Vitamin D (2000i.u.), and the jerking dramatically reduced. A few weeks later, I asked my doctor to check my Vitamin D levels, and while taking 2000i.u. daily, my Vitamin D levels were seriously abnormal (level 15). My doctor monitors my levels twice yearly now (53). Unfortunately, after 3 years of muscular peace, my muscles are once again jerking. Regardless, Vitamin D supplementation alleviated my depressive symptoms. Magnesium had an AMAZING calming effect on me as well (see mgwater.com for details). Your depression may be completely unrelated to Vitamin D, but I suggest your doctor runs the test as a precaution. If your doctor will not run the test, life extension has tests available online for purchase (reasonable price). They use a reputable lab. I found that proper diet and nutrition, exercise, and sleep play a DEFINITE role in my health (body and mind). I will pray for you, and something good will happen!