We understand your concern and are here to pray with you and provide biblical guidance. First, we want to address the use of the phrase "second ###" and ###. We are unclear what this is referring to. We assume it may be referring to a second son or second husband. We will refer to this individual as your relative for the remainder of the response. It is important to be clear when presenting a prayer request.
Let's turn to the Scriptures for guidance. The Bible clearly teaches us to avoid all forms of witchcraft and to trust in God's protection and provision. In Deuteronomy 18:10-12 WEB, it is written:
"There shall not be found with you anyone who makes his son or his daughter to pass through the fire, one who uses divination, one who practices sorcery, or an enchanter, or a sorcerer, or a charmer, or a consulter with a familiar spirit, or a wizard, or a necromancer. For whoever does these things is an abomination to Yahweh"
It is also written in Galatians 5:20-21 WEB as part of the works of the flesh:
"idolatry, sorcery, hatred, strife, jealousies, outbursts of anger, rivalries, divisions, heresies, envy, murders, drunkenness, orgies, and things like these; of which I forewarn you, even as I also forewarned you, that those who practice such things will not inherit the Kingdom of God."
We need to pray for your relative and this woman to turn away from any form of witchcraft and to trust in God's will for their lives. Moreover, it is important to remember that God hates covetousness. In Exodus 20:17 WEB, it is written:
"You shall not covet your neighbor's house. You shall not covet your neighbor's wife, nor his male servant, nor his female servant, nor his ox, nor his donkey, nor anything that is your neighbor's."
We also need to discuss the fact that sexual relations outside of marriage is fornication and a sin. It is important to pray that your relative and the woman repent of the sin of fornication and ask for forgiveness. It is written in Ephesians 5:3 WEB:
"But sexual immorality, and all uncleanness, or covetousness, let it not even be mentioned among you, as becomes saints"
Let us pray together:
Dear Heavenly Father,
We come before You in the name of Jesus Christ, lifting up our relative and this woman to You. We pray that You would break any ungodly ties between them and bring conviction to their hearts to turn away from any form of witchcraft and sin. We pray that You would protect the inheritance and thwart any plots to unrighteously acquire it. We ask that You would bring healing and restoration to their lives and lead them in the path of righteousness. We also pray for the repentance of sin and acceptance of Jesus Christ as Lord and Savior.
In Jesus' name, we pray. Amen.
We encourage you to continue praying for them and to trust in God's will for their lives. Remember that God is faithful and that He hears our prayers. It is also written in Psalm 55:22 WEB:
"Cast your burden on Yahweh, and he will sustain you.
He will never allow the righteous to be moved."
Trust fully in God and His promises. If the woman or your relative are casting spells, this is sin and is leading to death. It is very important to pray that God would have mercy on them and save them from this sin. Pray that they would both turn from this and trust fully in God.
Prayer Focus: God, Thank You for loving me. God, I ask You in Jesus’ name please bless me with everything that I stand in need of and everything You want me to have. 
