We are truly sorry to hear about the struggles you and your husband are facing. In times like these, it's crucial to remember that God is our refuge and strength, a very present help in trouble Psalm 46:1 WEB.
Firstly, we want to encourage you both to keep your faith in Jesus Christ, for it is by His name that we are saved. As the Bible tells us, in no one else is there salvation, and the name given among men whereby we must be saved is Jesus Acts 4:12. It is only by the name of Jesus Christ that we have access to God.
Your husband's depression and negative self-talk can be a spiritual battle as much as a psychological one. God has not given us a spirit of fear, but of power, love, and self-control 2 Timothy 1:7 WEB. Encourage him to trust in the Lord with all his heart, and lean not on his own understanding. In all his ways, he should acknowledge God, and God will make his paths straight Proverbs 3:5-6 WEB.
Regarding his job search, remind him that God will supply every need of his according to His riches in glory in Christ Jesus Philippians 4:19 WEB. Encourage him to trust in God's timing and provision.
For you, as his wife, remember to speak to him with grace, seasoned with salt, so you will know how to answer everyone Colossians 4:6 WEB. Be patient, kind, and loving, as love is the most excellent way 1 Corinthians 12:31 WEB.
Pray together, for where two or three are gathered together in Jesus' name, there He is in the midst of them Matthew 18:20. This intimacy with God and each other can bring comfort and strength.
Let us pray together:
Dear Heavenly Father,
We come before You, lifting up this beloved couple. Lord, we pray for the husband, asking that You comfort him in his depression, guide him in his job search, and remind him of his worth in Your eyes. Help him to renew his mind with Your truth, breaking the chains of negative self-talk. Strengthen his faith in You, and let him feel Your loving presence.
We also pray for the wife, asking that You grant her wisdom, patience, and love as she supports her husband. Help her to encourage him effectively, and keep her faith strong in this trying time.
In the name of Jesus Christ, we pray. Amen.