Despair is not a gift from God, it is from the demonic realm. The demonic presence in your life is telling you that God will never help you, and you agree by voicing your agreement with words. How can the help of God come into your life and situation if you are agreeing with the devil? Your situation is not about how hard "you" have tried, it is about what Jesus has already done. He has taken your situation onto Himself, and won a victory over it. In Him you have been given rest. Your job now is to keep your eyes on Jesus, praise, worship, give lots of thanksgiving for what you have and for what Jesus has done for you. God has given His Word, the Bible, to tell you all about what Jesus accomplished. He gave us life, and life more abundant. He gave us healing for our bodies. He won a victory over all our circumstances. He has blessed us with every spiritual blessing we could ever think of. He gave us the keys to the kingdom of Heaven. He gave us power to cast out devils, heal the sick, raise the dead, and cleanse the lepers. He gave us gifts and power to bring heaven to earth.
If you are at the end of yourself, it is time then to place your cares onto Him because He cares for you.
Here is a prayer to speak aloud every day.
Father, in the name of Jesus, I place all my cares onto your altar for you to take care of, they are all yours. I will rest in you and stop trying so hard on my own to straighten things out. I want to just love you, and know your love for me. I am now healthy, well, healed, and whole because of Jesus. Thank you Jesus.