We are truly sorry to hear about the trials and tribulations that have been weighing heavily upon you and your family. Firstly, we want to remind you that our battle is not against flesh and blood, but against the rulers, against the authorities, against the world powers of this darkness, against the spiritual forces of wickedness in the heavenly places. Therefore, take up the whole armor of God, that you may be able to withstand in the evil day, and having done all, to stand. Stand therefore, having the utility belt of truth buckled around your waist, and having put on the breastplate of righteousness, the shield of faith, the helmet of salvation, and the sword of the Spirit; being watchful and persistent in your prayer. (Ephesians 6:12-18 WEB)
In regards to the various situations you've mentioned, let's turn to the Word of God for guidance and encouragement.
We understand that you are struggling to pay debts and stay afloat financially. Be assured that God cares about our needs. We are reminded in Matthew 6:25-34. Therefore I tell you, don't be anxious for your life: what you will eat, or what you will drink; nor yet for your body, what you will wear. Isn't life more than food, and the body more than clothing? See the birds of the sky, that they don't sow, neither do they reap, nor gather into barns. Your heavenly Father feeds them. Aren't you of much more value than they? Which of you, by being anxious, can add one moment to his lifespan? Why are you anxious about clothing? Consider the lilies of the field, how they grow. They don't toil, neither do they spin, yet I tell you that even Solomon in all his glory was not dressed like one of these. But if God so clothes the grass of the field, which today exists, and tomorrow is thrown into the oven, won't he much more clothe you, you of little faith? Therefore don't be anxious, saying, 'What will we eat?', 'What will we drink?' or, 'With what will we be clothed?' For the Gentiles seek after all these things; for your heavenly Father knows that you need all these things. But seek first God's Kingdom, and his righteousness; and all these things will be given to you as well. Therefore don't be anxious for tomorrow, for tomorrow will be anxious for itself. Each day's own evil is sufficient.
Concerning your wife's drinking, remember that God calls us to be sober and self-controlled. It is written in 1 Peter 5:8, Be sober and self-controlled. Be watchful. Your adversary the devil, walks around like a roaring lion, seeking whom he may devour. We encourage you to seek godly counsel and support to help her overcome this struggle. Also, remember that although you may feel alone, we serve a God who is always with us and knows our struggles intimately.
Regarding your children and grandchildren, we are reminded to train up a child in the way he should go, and when he is old he will not depart from it. This is found in Proverbs 22:6. And the Lord Christ is the only example we should be following while being raised.
Remember also that the Lord tells us to cast all our anxiety on Christ because he cares for us in I Peter 5:6 and 7.
Lastly, we want to encourage you to keep praying and keep the faith. We are told in Galatians 6:9, Let us not be weary in doing good, for we will reap in due season, if we don't give up. Also, remember that our prayers should be directed to God the Father in the name of Jesus Christ, for it is written in John 14:6, Jesus said to him, I am the way, the truth, and the life. No one comes to the Father, except through me.
Let us pray together:
Dear Heavenly Father,
We come before You in the name of Jesus Christ, lifting up this beloved family who is facing numerous trials and tribulations. Lord, we know that You are faithful, and that You are the God of all comfort. We ask that You would strengthen their faith, and help them to hold onto hope, even in the darkest of times.
For the financial struggles, we know that You see their needs. We ask that You would open up the windows of heaven and pour out a blessing. Help them to be good stewards of their finances, and guide them in the path of financial wisdom and responsibility.
For their wife's struggle with drinking, Lord, we ask that You would set her free from this bondage. Help her to find her identity and worth in You alone, and give her the strength to overcome this stronghold. Surround her with godly support and accountability.
For their children and grandchildren, Lord, we ask that You would draw their hearts to You. Help them to know You personally, and to walk in Your ways. Give wisdom and guidance to their parents and grandparents as they seek to raise them in the fear and admonition of the Lord.
And finally, Father, we ask that You would lift up their hands which hang down, and strengthen their feeble knees. Help them to keep praying, and to not lose heart. Remind them of Your goodness, Your faithfulness, and Your unfailing love.
In Jesus Christ's name, we pray. Amen.
Prayer Focus: God, Thank You for loving me. God, I ask You in Jesus’ name please bless me with everything that I stand in need of and everything You want me to have. 
