We understand your concern for your best friend and his family, and we appreciate that you have brought this to us in Jesus' name. It's commendable that your friend has a big heart and has been a supportive friend to you. We will pray for his situation and also provide some biblical encouragement and advice.
Firstly, it's important to remember that God has a unique plan and timing for each person. It might feel like your friend is stagnant, but God may be working in his life in ways that are not immediately apparent.
We need to address a few things in your request. It's not good for a man to go through life alone. It is more understandable when they are seeking a wife and attempting to get one and not merely having a girlfriend. Have they been praying and asking God about becoming a godly husband?
1 Corinthians 7:1-2 WEB "Now concerning the things about which you wrote to me: it is good for a man not to touch a woman. But because of sexual immoralities, let each man have his own wife, and let each woman have her own husband."
The word girlfriend is not mentioned in the Bible and is a secular term.
It's also important to address the concern about your friend's living situation. In the Bible, we are called to honor our parents, but also, there comes a time when we should leave and cleave to our spouse.
Genesis 2:24 WEB "Therefore a man will leave his father and his mother, and will join with his wife, and they will be one flesh."
Let's pray for your friend and his family:
"Father, we come before you in Jesus' name to lift up our friend and his family. We pray for your guidance and provision in their lives. We ask that you would help your friend grow in wisdom and maturity, and that he would seek first your kingdom and your righteousness. We pray for your friend's siblings, that they would find godly spouses and build families that honor you.
We also pray for the safety and well-being of your friend's parents. We ask that you would provide a way for them to move to a safer location and that they would live in comfort and peace.
Lord, we ask that you would give your friend and his siblings a vision for their future, that they would set godly goals and work diligently to achieve them. We pray for your friend, that you would bring a godly woman into his life. We pray that you would help him to grow in confidence and purpose, that he would become the man you created him to be.
In Jesus' name, we pray. Amen."
Encourage your friend to seek God's will for his life and to trust in God's timing. Remind him that God is faithful and that He has a good plan and purpose for his life.
Proverbs 3:5-6 WEB "Trust in Yahweh with all your heart, and don’t lean on your own understanding. In all your ways acknowledge him, and he will make your paths straight."
Lastly, it's good that you mentioned Jesus' name in your prayer. It is by His name that we have access to God the Father, and it is only the name of Jesus that can save us.
John 14:6 WEB "Jesus said to him, “I am the way, the truth, and the life. No one comes to the Father, except through me."
Prayer Focus: God, Thank You for loving me. God, I ask You in Jesus’ name please bless me with everything that I stand in need of and everything You want me to have. 
